Allergen Details:
| Allergen name: | Hev b 4 |
|---|---|
| Allergen source: |
Major taxonomic group: Plantae Eudikotyledons Order: Malpighiales Species: Hevea brasiliensis (Para rubber tree (latex)) |
| Biochemical name: | Lecithinase homologue; GDSL lipase/esterase family member |
| MW(SDS-PAGE): | 53-55 kDa |
| Allergenicity: | - Pubmed:10691894: nHev b 4 bound IgE from 20 of 31 (65%) latex allergic health care workers and 10 of 13 (77%) patients with spina bifida in ELISA. - Pubmed:12642845: Of 62 health care workers who had experienced immediate skin reactions to NRL gloves, 39% had positive SPT response to purified nHev b 4. - Pubmed:16297147: Chemical deglycosylation of nHev b 4 abolished IgE binding of 3 latex allergic patients sera. |
| Allergenicity reference: | PubMed:10691894 PubMed:12642845 PubMed:16297147 |
| Route of allergen exposure: | Contact |
| Date Created: | 03-07-2003 |
| Last Updated: | 2019-07-17 18:36:53 |
| Submitter Info: | |
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Comments
| Isoallergen and variants | GenBank Nucleotide | GenBank Protein | UniProt | PDB |
|---|---|---|---|---|
| Hev b 4.0101 | AY437086 | AAR98518 | Q6T4P0 |