WHO/IUIS Allergen Nomenclature Sub-Committee

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Allergen Details:

Allergen name: Len c 2
Allergen source: Major taxonomic group: Plantae Eudikotyledons
Order: Fabales
Species: Lens culinaris (Lentil)
NCBI Taxomony ID: 3864
Biochemical name:Seed-specific biotinylated protein
Allergenicity:Of 22 lentil-allergic patients tested, 9 (41%) showed IgE binding to purified Len c 2 on immunoblot. IgE binding to Lentil extract was inhibited up to 45% by purified Len c 2 in CAP inhibition assay.
Allergenicity reference:PubMed:11080720
Route of allergen exposure:Food
Date Created:26-06-2003
Last Updated:2019-08-29 02:18:26
Submitter Info:
Submission Date:


Posted: 22 Jan 2016

No record of the submission, but based on the reference of Sanchez-Monge...Gabriel Salcedo, the peptide list and description, it is from their 2000 paper in JACI, v106:955-961. Note that they have only a few peptides from protease digested and semi-purified fragments that have high identity match to a pea biotinylated seed protein. Only pooled serum immunoblot is shown although claimed that 9 of 22 lentil allergic subjects bound to this protein, without clear description of method or results.

Table of IsoAllergens Click +/- for additional information
Isoallergen and variants GenBank Nucleotide GenBank Protein UniProt PDB
Len c 2.0101