WHO/IUIS Allergen Nomenclature Sub-Committee

Financial contributions from IUIS, EAACI, and AAAAI

Member Login

Allergen Details:

Allergen name: Lep d 2
Allergen source: Major taxonomic group: Animalia Arthropoda
Order: Sarcoptiformes
Species: Lepidoglyphus destructor (Storage mite)
NCBI Taxomony ID: 36936
Obsolete name:Lep d 1
Biochemical name:NPC2 family; MD-2-related lipid recognition (ML) domain containing protein
MW(SDS-PAGE):16 kDa (14 kDa non-red)
Allergenicity:Of 24 L.destructor-sensitive patients tested, 21 showed IgE binding to purified Lep d 2 in RAST. Good correlation between IgE binding to L. destructor and Lep d 2 (r=0.74,PLESSTHAN0.0001). >75% inhibition of IgE binding (serumpool) to Ld by Lep d 2.
Allergenicity reference:PubMed:1611545
Route of allergen exposure:Airway
Date Created:13-05-2003
Last Updated:2023-11-09 13:30:10
Submitter Info:
Submission Date:


Table of IsoAllergens Click +/- for additional information
Isoallergen and variants GenBank Nucleotide GenBank Protein UniProt PDB
Lep d 2.0101X81399 X83876 X89014CAA61419P80384 
Lep d 2.0102AJ487972CAD32313P80384 (variant) 
Lep d 2.0201X83875CAA58755P80384 (variant) 
Lep d 2.0202AJ487973CAD32314P80384 (variant)