Allergen Details:
| Allergen name: | Par j 1 |
|---|---|
| Allergen source: |
Major taxonomic group: Plantae Eudikotyledons Order: Rosales Species: Parietaria judaica (Pellitory of the wall) |
| Biochemical name: | Non-specific lipid transfer protein type 1 |
| MW(SDS-PAGE): | 15 kDa |
| Allergenicity: | Recombinant Par j 1 bound to IgE in 95% of the sera from Pj-allergic patients (n = 22)tested. rPar j 1 was capable of inducing histamine release from basophils of subjects allergic to Pj pollen (n=6), and Par j 1 was capable of inhibiting 40% of IgE binding to allergens in crude Pj pollen extract. |
| Allergenicity reference: | PubMed:9104791 PubMed:8137937 |
| Route of allergen exposure: | Airway |
| Date Created: | 22-04-2003 |
| Last Updated: | 2020-05-13 21:55:41 |
| Submitter Info: | |
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Comments
| Isoallergen and variants | GenBank Nucleotide | GenBank Protein | UniProt | PDB |
|---|---|---|---|---|
| Par j 1.0101 | X77414 | CAA54587 | P43217 | |
| Par j 1.0102 | X95867 | CAA65123 | O04404 | |
| Par j 1.0103 | AJ969433 | CAI94601 | Q1JTN5 | |
| Par j 1.0201 | X85012 | CAA59370 | Q40905 |