Allergen Details:
| Allergen name: | Ses i 1 |
|---|---|
| Allergen source: |
Major taxonomic group: Plantae Eudikotyledons Order: Lamiales Species: Sesamum indicum (Sesame) |
| Biochemical name: | 2S albumin |
| MW(SDS-PAGE): | 9 kDa |
| Allergenicity: | All ten sesame-allergic patients tested showed IgE binding to sesam antigens in immunoblot and had a positive skin prick test to sesame. The major, clinically most important allergen was the 9 kDa protein Ses i 1. This 9 kDa band identified by Pastorello et al. is the larger subunit of the 2S albumin. |
| Allergenicity reference: | PubMed:11419730 |
| Route of allergen exposure: | Food |
| Date Created: | 07-04-2003 |
| Last Updated: | 2018-08-01 23:43:43 |
| Submitter Info: | |
| Name: | Elida Pastorello |
| Institution: | |
| City: | |
| Email: | |
| Submission Date: | 2002-10-01 |
Comments
| Isoallergen and variants | GenBank Nucleotide | GenBank Protein | UniProt | PDB |
|---|---|---|---|---|
| Ses i 1.0101 | AF240005 | AAK15088 | Q9AUD1 |
There is a discrepancy in the MW of the 2S albumin from the Pastorello paper (9 kDa) with that predicted from whole sequence (17.5 kDa). This 2S albumin is presumably cut and appears differently in reducing gels. 1 August 2018