WHO/IUIS Allergen Nomenclature Sub-Committee

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Allergen Details:

Allergen name: Aed a 10
Allergen source: Major taxonomic group: Animalia Arthropoda
Order: Diptera
Species: Aedes aegypti (Yellow fever mosquito)
NCBI Taxomony ID: 7159
Biochemical name:Tropomyosin
Allergenicity:9 of 15 subjects allergic to Aedes aegypti had IgE binding to this tropomyosin
Allergenicity reference:PubMed:28235135
Route of allergen exposure:Airway
Date Created:28-05-2015
Last Updated:2019-07-20 18:13:47
Submitter Info:
Name:Jose Cantillo
Institution:Instituto de Investigaciones Inmunológicas-Universidad de Cartagena
City:Cartagena, Columbia
Submission Date:2015-05-28


Posted: 20 Jul 2019

First public presentation of allergenicity and IgE binding data as a poster presentation abstract in JACI v 133:abstract 354, 2014.
Publication in 2017 from Cantillo suggests patients sensitized to mosquito tropomyosin react via airway exposure.

Table of IsoAllergens Click +/- for additional information
Isoallergen and variants GenBank Nucleotide GenBank Protein UniProt PDB
Aed a 10.0101XM_001655904.1XP_001655954.1Q17H75 
Aed a 10.0201XM_001655898.1XP_001655948.1Q17H80