WHO/IUIS Allergen Nomenclature Sub-Committee

Financial contributions from IUIS, EAACI, and AAAAI

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Allergen Details:

Allergen name: Cha o 3
Allergen source: Major taxonomic group: Plantae Pinopsida
Order: Cupressales
Species: Chamaecyparis obtusa (Japanese cypress)
NCBI Taxomony ID: 13415
Biochemical name:Cellulase (glycosyl hydrolase)
Allergenicity:Fourteen of 16 Japanese pollen allergic subjects showed IgE binding to the pure protein in ELISA. Three of four had basophil activation (CD203c) positivity. All of these subjects were RAST class >2 positive. The 2016 publication in JACI demonstrates T cell reactivity as well as basophil activation.
Allergenicity reference:PubMed:27237746
Route of allergen exposure:Airway
Date Created:25-08-2015
Last Updated:2019-07-31 00:15:30
Submitter Info:
Name:Toshihiro Osada
Institution:Taiho Pharmaceutical Co. Ltd
City:Ibaraki, Japan
Submission Date:2015-07-29


Posted: 27 Aug 2015

Note the nucleotide sequence was patented under the Genbank accession HV942721, so BLAST does not find the sequence. The sequence is published here with permission of the submitter.

Table of IsoAllergens Click +/- for additional information
Isoallergen and variants GenBank Nucleotide GenBank Protein UniProt PDB
Cha o 3.0101HV942721GH5FP_CHAOBC0HLA0