Allergen Details
| Allergen name: | Bla g 9 |
|---|---|
| Allergen source: |
Major taxonomic group: Animalia Arthropoda Order: Blattodea Species: Blattella germanica (German cockroach) NCBI Taxomony ID: 6973 |
| Biochemical name: | Arginine kinase |
| MW(SDS-PAGE): | 40 kDa |
| Allergenicity: | Two studies including this data by A Pomés with 10 of 23 subjects (43.5%) who were positive by case history for airway allergy, and positive by SPT with extract of Blatella germanica having also positive IgE by ImmunoCAP using Picchia produced recombinant Bla g 9 as the target (not yet published). Study by Chuang et al., 2010 with more than 7 subjects from Taiwan (>34%) with allergy and cockroach specific IgE being clearly positive by solid-phased immunobinding with native protein. A third study by Dillon et al., PMID 26414909 identified Th2 epitopes using cells from allergic subjects. |
| Allergenicity reference: | PubMed:20960453 |
| Route of allergen exposure: | Airway |
| Created: | 2017-01-14 10:27:01 |
| Last Updated: | 2020-03-23 21:53:09 |
| Submitter Info: | |
| Name: | Anna Pomés |
| Institution: | Indoor Biotechnologies, Inc. |
| City: | Charlottesville, VA USA |
| Email: | apomes@inbio.com |
| Submission Date: | 2017-01-06 |
Comments
Table of Isoallergens
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| Isoallergen and variants | GenBank Nucleotide | GenBank Protein | UniProt | PDB |
|---|---|---|---|---|
| Bla g 9.0101 | DQ358231.1 | ABC86902 |