Allergen Details:
| Allergen name: | Per a 5 |
|---|---|
| Allergen source: |
Major taxonomic group: Animalia Arthropoda Order: Blattodea Species: Periplaneta americana (American cockroach) |
| Biochemical name: | Glutathione S-transferase |
| MW(SDS-PAGE): | 23 kDa |
| Allergenicity: | Positive IgE tests with 15 of 15 cockroach allergic patients showing positive binding to natural and recombinant protein, with negative responses from 5 of 5. IgE binding tested by dot blot and ELISA. Subjects positive by SPT. NOTE:this submission was from Thailand in 2017, there was a previous paper by Wei et al., 2014 that showed IgE binding and basophil activity to a 98% identical sequence that Wei called Per a 5. That is now added as Per a 5.0102. |
| Route of allergen exposure: | Airway |
| Date Created: | 31-10-2017 |
| Last Updated: | 2020-03-24 19:28:20 |
| Submitter Info: | |
| Name: | Nitat Sookrung |
| Institution: | Faculty of Medicine, Siriraj Hospital, Mahidol University Dept. of Research |
| City: | Bangkok, Thailand |
| Email: | nitat.soo@mahidol.ac.th |
| Submission Date: | 2017-10-02 |
Comments
| Isoallergen and variants | GenBank Nucleotide | GenBank Protein | UniProt | PDB |
|---|---|---|---|---|
| Per a 5.0101 | MG255130 | |||
| Per a 5.0102 | AEV23867 |