WHO/IUIS Allergen Nomenclature Sub-Committee

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Allergen Details:

Allergen name: Per a 5
Allergen source: Major taxonomic group: Animalia Arthropoda
Order: Blattodea
Species: Periplaneta americana (American cockroach)
NCBI Taxomony ID: 6978
Biochemical name:Glutathione S-transferase
Allergenicity:Positive IgE tests with 15 of 15 cockroach allergic patients showing positive binding to natural and recombinant protein, with negative responses from 5 of 5. IgE binding tested by dot blot and ELISA. Subjects positive by SPT. NOTE:this submission was from Thailand in 2017, there was a previous paper by Wei et al., 2014 that showed IgE binding and basophil activity to a 98% identical sequence that Wei called Per a 5. That is now added as Per a 5.0102.
Route of allergen exposure:Airway
Date Created:31-10-2017
Last Updated:2020-03-24 19:28:20
Submitter Info:
Name:Nitat Sookrung
Institution:Faculty of Medicine, Siriraj Hospital, Mahidol University Dept. of Research
City:Bangkok, Thailand
Submission Date:2017-10-02


Table of IsoAllergens Click +/- for additional information
Isoallergen and variants GenBank Nucleotide GenBank Protein UniProt PDB
Per a 5.0101MG255130   
Per a 5.0102 AEV23867