WHO/IUIS Allergen Nomenclature Sub-Committee

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Allergen Details:

Allergen name: Ole e 12
Allergen source: Major taxonomic group: Plantae Eudikotyledons
Order: Lamiales
Species: Olea europaea (Olive)
NCBI Taxomony ID: 4146
Biochemical name:Isoflavone reductase
Allergenicity:Twenty two patients out of 63 recruited with peach allergy also had olive pollen sensitization. These were tested for IgE binding to recombinant E. coli produced protein by ELISA. Earlier work had shown IgE binding to this protein from a different subject as early as 2008. Natural protein was also purified and proteomics demonstrated it was the same protein and had IgE binding in 2D gel blots.
Allergenicity reference:PubMed:26391288
Route of allergen exposure:Airway
Created:2018-04-04 18:32:54
Last Updated:2019-09-04 23:35:48
Submitter Info:
Name:Maria Teresa Villalba, Lourdes Castro
Institution:Comlutense University of Madrid Biochemistry, ALK-Abello
City:Madrid, Spain,
Submission Date:2018-03-02


Table of IsoAllergens Click +/- for additional information
Isoallergen and variants GenBank Nucleotide GenBank Protein UniProt PDB
Ole e 12.0101EU927297.1ACL13551.1E1U332