Allergen Details:
| Allergen name: | Asc l 5 |
|---|---|
| Allergen source: |
Major taxonomic group: Animalia Nematoda Order: Ascaridida Species: Ascaris lumbricoides (Common roundworm) NCBI Taxomony ID: 6252 |
| Obsolete name: | Divalent cation binding protein |
| MW(SDS-PAGE): | 14 kDa |
| Allergenicity: | 13 of 26 subjects with Ascaris lumbricoides infection and allergy were positive by IgE binding to recombinant protein produced by cDNA clone. 81 non-infected people were negative. 3 of 5 subjects had positive basophil resonses to this protein, measured by CD203c positivity by flow cytometry. |
| Allergenicity reference: | Allergy abstracts of EAACI meeting in Barcelona abstract PubMed:13 in Allergy PubMed:70 (Supple 101) Manotas M. Zakzuk J. Coronado S. Ahumada V and Caraballo L. |
| Route of allergen exposure: | Food |
| Created: | 2019-10-17 10:18:00 |
| Last Updated: | 2019-10-17 11:10:25 |
| Submitter Info: | |
| Name: | Luis Caraballo |
| Institution: | Institute for Immunological Research, University of Cartagena |
| City: | Cartagena, Columbia |
| Email: | lcaraballog@unicartagena.edu.co |
| Submission Date: | 2019-08-14 |
Comments
| Isoallergen and variants | GenBank Nucleotide | GenBank Protein | UniProt | PDB |
|---|---|---|---|---|
| Asc l 5.0101 | MN275230 | MN275230 |