Allergen Nomenclature Publications
Official papers published by the WHO/IUIS Allergen Nomenclature Sub-Committee
Other nomenclature-related papers by members of the sub-committee
The first WHO/IUIS allergen nomenclature was published in 1986 by the founding members of
the committee. A revision reflecting the current allergen nomenclature was published in
1994/5 in several journals, along with an editorial outlining the changes made in the
revised nomenclature. Later, the sub-committee also published minor updates of the
nomenclature, specifications of allergen submission guidelines as well as updates of names
for specific groups of allergens. You will also find below other nomenclature-related
articles published by members of the sub-committee.
Official papers published by the WHO/IUIS Allergen Nomenclature Sub-Committee
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Platts-Mills TA, Hilger C, Jappe U, van Hage M, Gadermaier G, Spillner E, Lidholm J,
Keshavarz B, Aalberse RC, van Ree R, Goodman RE, Pomés A. Carbohydrate
epitopes currently recognized as targets for IgE antibodies.
Allergy 2021; 76: 2383-94; doi:
10.1111/all.14802.
Free full text at PubMed Central
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A summary of carbohydrate epitopes that are involved in IgE binding and their clinical
relevance. IgE binging glycans are classified into five groups (A-E). A summary of this paper
is also included on the allergen nomenclature wesite, see Carbohydrate epitopes.
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Chan SK, Pomés A, Hilger C, Davies JM, Mueller G, Kuehn A, Lopata AL, Gadermaier G, van Hage M,
Raulf M, Goodman RE, on behalf of the WHO IUIS Allergen Nomenclature Sub-Committee.
Keeping Allergen Names Clear and Defined.
Front Immunol 2019; 10: 2600, doi:
10.3389/fimmu.2019.02600 (open access).
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This report summarizes recent developments that led to updates in classification of
cockroach group 1 and 5 allergens, heterodimeric secretoglobulins and IgE-binding glycans.
Moreover, an overview of respiratory allergens from pollen and fungi and of occupational
food allergens is provided.
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Pomés A, Davies JM, Gadermaier G, Hilger C, Holzhauser T, Lidholm J, Lopata AL, Mueller GA,
Nandy A, Radauer C, Chan SK, Jappe U, Kleine-Tebbe J, Thomas WR, Chapman MD, van Hage M,
van Ree R, Vieths S, Raulf M, Goodman RE, on behalf of the WHO IUIS Allergen Nomenclature
Sub-Committee. WHO/IUIS Allergen Nomenclature: Providing a common
language. Mol Immunol 2018; 100: 3-13, doi:
10.1016/j.molimm.2018.03.003 (open access).
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A review of criteria for the acceptance of a proteins as an allergen to be included in the
WHO/IUIS Allergen Nomenclature Database
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Radauer C, Nandy A, Ferreira F, Goodman RE, Larsen JN, Lidholm J, Pomés A, Raulf-Heimsoth M,
Rozynek P, Thomas WR, Breiteneder H. Update of the WHO/IUIS Allergen
Nomenclature Database based on analysis of allergen sequences.
Allergy 2014; 69: 413-9, doi:
10.1111/all.12348 (open access).
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A summary of updates of allergen names approved at the meetings of the committee in 2011
through 2013 (e.g. renaming allergens from ragweed pollen and peanut and isoallergens of
Bet v 1), reflecting progress in identification, cloning, and sequencing of allergens.
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Larsen JN, Lowenstein H. Allergen Nomenclature.
J Allergy Clin Immunol 1996; 97: 577-8,
doi: 10.1016/s0091-6749(96)70301-9
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An editorial describing the changes made in the 1994 nomenclature
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King TP, Hoffman D, Lowenstein H, Marsh DG, Platts-Mills TAE, Thomas W.
Allergen nomenclature. IUIS/WHO Allergen Nomenclature Subcommittee.
Bull World Health Organ 1994; 72: 797-806
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The revised allergen nomenclature guidelines published in 1994. This naming system is still
valid today. This article was also published in the
J Allergy Clin Immunol,
Allergy,
Int Arch Allergy Immunol and
Clin Exp Allergy.
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Marsh DG, Goodfriend L, King TP, Lowenstein H, Platts-Mills TA. Allergen
nomenclature. Bull World Health Organ 1986; 64: 767-74
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The original allergen nomenclature guidelines, which were revised in 1995
Other nomenclature-related publications by members of the sub-committee
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Sudharson S, Kalic T, Hafner C, Breiteneder H. Newly defined allergens
in the WHO/IUIS Allergen Nomenclature Database during 01/2019-03/2021.
Allergy 2021; 76: 3359-73; doi:
10.1111/all.15021 (open access).
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Breiteneder H, Goodman R, Chapman MD, Pomés A. Allergen Nomenclature.
In: Lockey RF, Ledford DK (eds): Allergens and Allergen Immunotherapy for Allergic
Diseases, Subcutaneous, Sublingual and Oral, 6th edition. CRC Press/Taylor & Francis Group,
New York, NY, USA, 2020, pp 49-63,
doi: 10.1201/9781351208994.
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Goodman RE, Breiteneder H. The WHO/IUIS Allergen Nomenclature.
Allergy 2019; 74: 429-31; doi:
10.1111/all.13693.
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Jappe U, Breiteneder H. Peanut allergy - Individual molecules as a key
to precision medicine. Allergy 2019; 74: 216-9; doi:
10.1111/all.13625
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Kleine-Tebbe J, Hamilton RG, Goodman RE. Cockroach allergens: Coping
with challenging complexity. J Allergy Clin Immunol
2019; 143: 1342-4; doi:
10.1016/j.jaci.2019.01.028.
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Radauer C. Nomenclature of Food Allergens. In: Lopata AL (ed.):
Food Allergy - Molecular and Clinical Practice, 1st edition. CRC Press, Boca Raton, Florida,
United States; 2017. p. 30-40; doi: 10.1201/9781315120126.
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Breiteneder H, Chapman MD. Allergen Nomenclature. In: Lockey RF,
Ledford DK (eds): Allergens and Allergen Immunotherapy: Subcutaneous, sublingual and oral.
5th Edition. CRC Press, Taylor & Francis Group, Boca Raton, Florida, USA, 2014, pp 37-49,
doi: 10.1201/b16539.
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Breiteneder H. Protein families: implications for allergen nomenclature,
standardisation and specific immunotherapy. Arb Paul Ehrlich
Inst Bundesinstitut Impfstoffe Biomed Arzneim 2009; 96: 249-54.
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Chapman MD. Allergen Nomenclature. In: Lockey RF, Ledford DK (eds.):
Allergens and Allergen Immunotherapy. 4th edition, CRC Press, Boca Raton, FL, USA, 2008, pp 47-58;
doi: 10.3109/9781420061987.
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Chapman MD, Pomés A, Breiteneder H, Ferreira F. Nomenclature and structural
biology of allergens. J Allergy Clin Immunol 2007; 119:
414-20; doi: 10.1016/j.jaci.2006.11.001.
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