ALLERGEN NOMENCLATURE
WHO/IUIS Allergen Nomenclature Sub-Committee

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Allergen Details:

Allergen name: Tyr p 20
Allergen source: Major taxonomic group: Animalia Arthropoda
Order: Astigmata
Species: Tyrophagus putrescentiae (Storage mite)
Biochemical name:Arginine kinase
MW(SDS-PAGE):40 kDa
Allergenicity:298 subjects attending the Taichung Veterans General Hospital were recruited with at least asthma, rhinitis, atopic dermatitis or eczema. They were tested by SPT and ELISA to recombinant Tyr p 20.0101, which had been cloned by PCR. Indirect basophil activation was tested. 51 of 298 were positive for IgE binding by ELISA, 45 of 106 were positive by SPT and 25 of 30 positive by basophil activation.
Allergenicity reference:PubMed:32887361
Route of allergen exposure:Airway
Date Created:2020/9/8
Last Updated:2022-04-13 16:29:32
Submitter Info:
Name:En-Chih Liao
Institution:Mackay Medical College
City:Taipei City, Taiwan
Email:enchih@mmc.edu.tw
Submission Date:2020-08-26

Comments

Posted: 13 Sep 2020

cDNA sequence and predicted AA sequence in submission. Not for public view until published. High identity to Der p 20, Blo t 20. two peptides of recombinant protein determined by LC-MSMS.

Table of IsoAllergens Click +/- for additional information
Isoallergen and variants GenBank Nucleotide GenBank Protein UniProt PDB
Tyr p 20.0101MT900252QOI58528A0A868BHP5 
Tyr p 20.0201MZ824392