ALLERGEN NOMENCLATURE
WHO/IUIS Allergen Nomenclature Sub-Committee

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Allergen Details:

Allergen name: Hev b 1
Lineage: Source: Plantae Magnoliopsida
Order: Malpighiales
Species: Hevea brasiliensis (Para rubber tree (latex))
Biochemical name:Rubber elongation factor
MW(SDS-PAGE):14
Allergenicity:- Of 140 patients with spina bifida (SB), 81% had IgE against Hev b 1, as measured by EAST. Of 105 health care workers allergic to latex, 52% had Hev b 1 specific IgE. - None of the 20 latex-allergic patients tested showed IgE binding to nHev b 1 or rHev b 1 on immunoblot. However, both allergens were recognized by 2 serumpools of patients with SB: medline 96426247. - Hev b 1 was recognized by 18 out of 21 patients with SB, but only by 2 of 14 patients with latex-allergy: medline 94004042
Allergenicity ref.:9389300
Food allergen:No
Date Created:2003-07-03 12:00:00
Last Updated:2010-04-29 16:57:55
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Table of IsoAllergens:

Isoallergen and variants GenBank Nucleotide GenBank Protein UniProt PDB
Hev b 1.0101X56535CAA39880P15252