Allergen Details:
| Allergen name: | Hev b 1 |
|---|---|
| Allergen source: |
Major taxonomic group: Plantae Eudikotyledons Order: Malpighiales Species: Hevea brasiliensis (Para rubber tree (latex)) NCBI Taxomony ID: 3981 |
| Biochemical name: | Rubber elongation factor |
| MW(SDS-PAGE): | 14 kDa |
| Allergenicity: | PubMed:9389300: Of 140 patients with spina bifida (SB), 81% had IgE against nHev b 1, as measured by EAST. Of 105 health care workers (HCWs) allergic to latex, 52% had nHev b 1 specific IgE. In skin-prick test with nHev b 1, 10 of 14 patients with SB and 16 of 18 HCWs reacted to the allergen. - PubMed:8828541: None of 20 tested sera of latex-allergic adult patients tested showed IgE binding to nHev b 1 or rHev b 1 on immunoblot. However, both allergens were recognized by 2 serum pools (53 and 101 sera) of patients with SB. - PubMed:10691894: Hev b 1 was recognized in an IgE-ELISA by 10 of 31 (32%) sera from latex allergic HCWs and from 13 of 13 sera from latex allergic patients with SB. |
| Allergenicity reference: | PubMed:9389300 PubMed:8828541 PubMed:10691894 |
| Route of allergen exposure: | Contact |
| Date Created: | 03-07-2003 |
| Last Updated: | 2019-07-11 17:58:01 |
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Comments
| Isoallergen and variants | GenBank Nucleotide | GenBank Protein | UniProt | PDB |
|---|---|---|---|---|
| Hev b 1.0101 | X56535 | CAA39880 | P15252 |